ملخصات الابحاث

المجالات البحثية

Homology modelling and drug design
RP-HPLC method for the simultaneous determination of omeprazole, tinidazole and doxycycline mixture in the presence of omeprazole and tinidazole degradation products
Spectrophotometric determination of omeprazole sodium and rantidine hydrochloride using 2,4-dinitrofluorobenzene and 4-chloro-7-nitrobenz-2-oxa-1,3-diazole accompanied with a kinetic study
Spectrophotometric determination of omeprazole via nitrosation reaction
Spectrophotometric determination of ranitidine and famotidine using 1,2-naphthoquinone sulphonate
Validated spectophotometric determination of pantoprazole sodium in tablets using 2,4-dinitrofluorobenzene through nucleophilic substitution reaction

الابحاث العلمية

1 - The anti-inflammatory drugs diclofenac and ketorolac inhibit urease activity and biofilm formation by uropathogenic Proteus mirabilis (2025).

2 - Inhibition of metallo-β-lactamases in carbapenem resistant Gram negative bacilli by omeprazole and pantoprazole (2025).

3 - Novel 2-[thio]acetamide linked quinazoline/1,2,4-triazole/chalcone hybrids: Design, synthesis, and anticancer activity as EGFR inhibitors and apoptotic inducers (2024).

4 - Various techniques for resolving overlapping ultraviolet spectra of combination pharmaceutical dosage forms containing hydroxychloroquine and paracetamol (2024).

5 - Utilization of zein nano-based system for promoting antibiofilm and anti-virulence activities of curcumin against Pseudomonas aeruginosa (2024).

6 - Instrumental analytical techniques for evaluating some anti-infective drugs in pharmaceutical products and biological fluids (2024).

7 - Different instrumental techniques for analysis of some gastrointestinal tract drugs (2024).

8 - Design and Synthesis of Novel Phenylalanine tRNA Synthetase Inhibitors as Potential Therapeutics for the Treatment of MRSA Infections (2024).

9 - Design and Synthesis of Novel Azoles-Containing Compounds for Biological Evaluation (2024).

10 - Casuarina glauca branchlets' extract as a potential treatment for ulcerative colitis: chemical composition, in silico and in vivo studies (2023).

11 - Exploitation of multi-walled carbon nanotubes/ Cu(II)-metal organic framework based glassy carbon electrode for the determination of orphenadrine citrate (2023).

12 - Developing a highly validated and sensitive HPLC method for simultaneous estimation of cefotaxime and paracetamol in pure and pharmaceutical preparations (2023).

13 - Different methods for resolving overlapping UV spectra of combination medicinal dose forms of ciprofloxacin and metronidazole (2023).

14 - Design, synthesis, in vitro and in silico evaluation of novel substituted 1,2,4-triazole analogues as dual human VEGFR-2 and TB-InhA inhibitors (2023).

15 - Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation (2023).

16 - Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation (2023).

17 - Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential (2023).

18 - Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential (2023).

19 - Chamaecyparis lawsoniana Leaf Essential Oil as a Potential Anticancer Agent: Experimental and Computational Studies (2023).

20 - Targeting Mycobacterium tuberculosis: Synthesis, in vitro and in silico evaluation of novel N1-(benzo[d]oxazol-2-yl)-N4-arylidine compounds (2023).

21 - Synergistic Benefits: Exploring the Anti-Virulence Effects of Metformin/Vildagliptin Antidiabetic Combination against Pseudomonas aeruginosa via Controlling Quorum Sensing Systems (2023).

22 - Design and synthesis of uracil/thiouracil based quinoline scaffolds as topoisomerases I&II inhibitors for chemotherapy: A new hybrid navigator with DFT calculation (2023).

23 - Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria (2023).

24 - Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria (2023).

25 - Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation (2023).

26 - Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate (2023).

27 - Schiff bases as linker in the development of quinoline-sulfonamide hybrids as selective cancer-associated carbonic anhydrase isoforms IX/XII inhibitors: A new regioisomerism tactic (2022).

28 - Characterization of the Anti-Biofilm and Anti-Quorum Sensing Activities of the β-Adrenoreceptor Antagonist Atenolol against Gram-Negative Bacterial Pathogens (2022).

29 - Agathis robusta Bark Extract Protects from Renal Ischemia-Reperfusion Injury: Phytochemical, In Silico and In Vivo Studies (2022).

30 - Silencing of Salmonella typhimurium Pathogenesis: Atenolol Acquires Efficient Anti-Virulence Activities (2022).

31 - Muting Bacterial Communication: Evaluation of Prazosin Anti-Quorum Sensing Activities against Gram-Negative Bacteria Pseudomonas aeruginosa, Proteus mirabilis, and Serratia marcescens (2022).

32 - Agathis robusta Bark Essential Oil Effectiveness against COVID-19: Chemical Composition, In Silico and In Vitro Approaches (2022).

33 - Design, synthesis and microbiological evaluation of novel compounds as potential Staphylococcus aureus phenylalanine tRNA synthetase inhibitors (2018).

34 - Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach (2017).

35 - A homology model of Staphylococcus aureus phenylalanine tRNA synthetase: Active site analysis and docking interactions (2016).

36 - Spectrophotometric determination of omeprazole via nitrosation reaction (2014).

37 - Spectrophotometric determination of omeprazole sodium and rantidine hydrochloride using 2,4-dinitrofluorobenzene and 4-chloro-7-nitrobenz-2-oxa-1,3-diazole accompanied with a kinetic study (2014).

38 - RP-HPLC method for the simultaneous determination of omeprazole, tinidazole and doxycycline mixture in the presence of omeprazole and tinidazole degradation products (2014).

39 - Validated spectophotometric determination of pantoprazole sodium in tablets using 2,4-dinitrofluorobenzene through nucleophilic substitution reaction (2014).

40 - Spectrophotometric determination of ranitidine hydrochloride and famotidine using 1,2- naphthoquinone-4-sulphonate (2013).

المجالات البحثية

الابحاث العلمية

تسجيل الدخول

صفحاتنا

الدعم الفنى

إتصل بنا